2-Heptyl-3-hydroxy-4(1H)-quinolinone

Names

[ Name ]:
2-Heptyl-3-hydroxy-4(1H)-quinolinone

[Synonym ]:
2-Heptyl-3-hydroxy-4(3H)-quinolinone
2-heptyl-3-hydroxy-4-quinolone
2-heptyl-3-hydroxyl-4(1H)-quinolone
2-Heptyl-3-hydroxyquinolin-4(1H)-one
Pseudomonas quinolone signal
4(1H)-Quinolinone, 2-heptyl-3-hydroxy-
3,4-dihydroxy-2-heptylquinoline
2-Heptyl-3-hydroxy-4(1H)-quinolinone
2-Heptyl-3-hydroxyl-4-quinolone
4(3H)-Quinolinone, 2-heptyl-3-hydroxy-
2-Heptyl-3-hydroxy-4(1H)-quinolone

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
416.8±45.0 °C at 760 mmHg

[ Melting Point ]:
182-185ºC

[ Molecular Formula ]:
C₁₆H₂₁NO₂

[ Molecular Weight ]:
259.343

[ Flash Point ]:
205.9±28.7 °C

[ Exact Mass ]:
259.157227

[ PSA ]:
53.09000

[ LogP ]:
2.93

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.568

Safety Information

[ Hazard Statements ]:
H413

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933499090

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa.

Proc. Natl. Acad. Sci. U. S. A. 20th ed., 96 , 11229-11234, (1999)

Numerous species of bacteria use an elegant regulatory mechanism known as quorum sensing to control the expression of specific genes in a cell-density dependent manner. In Gram-negative bacteria, quor...

3-indolylacetonitrile decreases Escherichia coli O157:H7 biofilm formation and Pseudomonas aeruginosa virulence.

Environ. Microbiol. 13 , 62-73, (2011)

Intercellular signal indole and its derivative hydroxyindoles inhibit Escherichia coli biofilm and diminish Pseudomonas aeruginosa virulence. However, indole and bacterial indole derivatives are unsta...

The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ and PQS play multifunctional roles in quorum sensing and iron entrapment.

Chem. Biol. 14 , 87-96, (2007)

Pseudomonas aeruginosa produces 2-heptyl-3-hydroxy-4(1H)-quinolone (PQS), a quorum-sensing (QS) signal that regulates numerous virulence genes including those involved in iron scavenging. Biophysical ...