2-Methoxyethanamine

Names

[ CAS No. ]:
109-85-3

[ Name ]:
2-Methoxyethanamine

[Synonym ]:
2-Methoxyethanamine
2-MethoxyethylaMine
2-Aminoethyl Methyl Ether
MFCD00008180
Ethanamine, 2-methoxy-
O-Methylethanolamine
EINECS 203-712-1

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
95.0±0.0 °C at 760 mmHg

[ Melting Point ]:
-82 °C

[ Molecular Formula ]:
C₃H₉NO

[ Molecular Weight ]:
75.110

[ Flash Point ]:
9.4±0.0 °C

[ Exact Mass ]:
75.068413

[ PSA ]:
35.25000

[ LogP ]:
-0.65

[ Vapour Pressure ]:
46.3±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.397

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KR8750000

CHEMICAL NAME :: Ethylamine, 2-methoxy-

CAS REGISTRY NUMBER :: 109-85-3

BEILSTEIN REFERENCE NO. :: 0741854

LAST UPDATED :: 199712

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C3-H9-N-O

MOLECULAR WEIGHT :: 75.13

WISWESSER LINE NOTATION :: Z2O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546426 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546426

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546426

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

Safety Information

[ Symbol ]:

GHS02, GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H314

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Highlyflammable;C:Corrosive;

[ Risk Phrases ]:
R11;R35

[ Safety Phrases ]:
S16-S26-S36/37/39-S45

[ RIDADR ]:
UN 2733 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
KR8750000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Large steric effect in the substitution reaction of amines with phosphoimidazolide-activated nucleosides.

J. Org. Chem. 60(3) , 632-7, (1995)

Aliphatic amines react with phosphoimidazolide-activated derivatives of guanosine and cytidine (ImpN) by replacing the imidazole group. The kinetics of reaction of guanosine 5'-phospho-2-methylimidazo...

Supramolecular motifs in dynamic covalent PEG-hemiaminal organogels.

Nat. Commun. 6 , 7417, (2015)

Dynamic covalent materials are stable materials that possess reversible behaviour triggered by stimuli such as light, redox conditions or temperature; whereas supramolecular crosslinks depend on the e...