Di-tert-butyl peroxide

Names

[ CAS No. ]:
110-05-4

[ Name ]:
Di-tert-butyl peroxide

[Synonym ]:
1X1&1&OOX1&1&1
2,2'-dioxybis(2-methylpropane)
Di-tert-butyl peroxide
EINECS 203-733-6
2-Methyl-2-[(2-methyl-2-propanyl)peroxy]propane
Peroxide, bis(1,1-dimethylethyl)
2-tert-butylperoxy-2-methylpropane
2-(tert-Butylperoxy)-2-methylpropane
di-tert-butylperoxide
MFCD00008803
Bis(1,1-dimethylethyl) peroxide
di-t-butyl peroxide
tert-butyl peroxide
DTBP
tert-Butyl peroxide (Luperox DI)

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
111.0±0.0 °C at 760 mmHg

[ Melting Point ]:
-30 °C

[ Molecular Formula ]:
C₈H₁₈O₂

[ Molecular Weight ]:
146.227

[ Flash Point ]:
29.7±25.6 °C

[ Exact Mass ]:
146.130676

[ PSA ]:
18.46000

[ LogP ]:
3.19

[ Vapour Pressure ]:
27.3±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.405

[ Stability ]:
May decompose explosively if heated, subjected to shock, or treated with reducing agents. Highly flammable. Refrigerate.

[ Water Solubility ]:
immiscible

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ER2450000

CHEMICAL NAME :: tert-Butyl peroxide

CAS REGISTRY NUMBER :: 110-05-4

LAST UPDATED :: 199710

DATA ITEMS CITED :: 16

MOLECULAR FORMULA :: C8-H18-O2

MOLECULAR WEIGHT :: 146.26

WISWESSER LINE NOTATION :: 1X1&1&OOX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,263,1986

TYPE OF TEST :: Rinsed with water

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: ZAARAM Zentralblatt fuer Arbeitsmedizin und Arbeitsschutz. (Darmstadt, Fed. Rep. Ger.) V.1-25, 1951-75. Volume(issue)/page/year: 8,25,1958 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >25 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARCOC* ARCO Chemical Company Report. (3801 West Chester Pike, Newton Square, PA 19073) Volume(issue)/page/year: JUN1982

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >4100 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARCOC* ARCO Chemical Company Report. (3801 West Chester Pike, Newton Square, PA 19073) Volume(issue)/page/year: JUN1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3210 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4572 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,43,1982

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4103 ppm/4H

TOXIC EFFECTS :: Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 105 gm/kg/7W-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 585 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - lymphoma, including Hodgkin's disease

REFERENCE :: RARSAM Radiation Research, Supplement. (New York, NY) No.1-7, 1959-67. Discontinued. Volume(issue)/page/year: 3,193,1963 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 226 mg/m3/4H

SEX/DURATION :: female 1-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(12),46,1976 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 100 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0478 No. of Facilities: 100 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 872 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0478 No. of Facilities: 1178 (estimated) No. of Industries: 26 No. of Occupations: 30 No. of Employees: 20561 (estimated) No. of Female Employees: 6371 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H242-H341-H412

[ Precautionary Statements ]:
P210-P220-P273-P280-P410-P411 + P235

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11;R7

[ Safety Phrases ]:
S14-S16-S3/7-S36/37/39-S14A

[ RIDADR ]:
UN 3107 5.2

[ WGK Germany ]:
1

[ RTECS ]:
ER2450000

[ Packaging Group ]:
II

[ Hazard Class ]:
5.2

[ HS Code ]:
2909600000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909600000

[ Summary ]:
2909600000 alcohol peroxides, ether peroxides, ketone peroxides and their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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