trioxane

Names

[ CAS No. ]:
110-88-3

[ Name ]:
trioxane

[Synonym ]:
1,3,5-Trioxane
s-Trioxane
Metaformaldehyde
MFCD00006563
EINECS 203-812-5
trioxane

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
114.5±0.0 °C at 760 mmHg

[ Melting Point ]:
59-62 °C(lit.)

[ Molecular Formula ]:
C₃H₆O₃

[ Molecular Weight ]:
90.078

[ Flash Point ]:
45.0±0.0 °C

[ Exact Mass ]:
90.031693

[ PSA ]:
27.69000

[ LogP ]:
-0.62

[ Vapour Pressure ]:
23.5±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.385

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
221 g/L (25 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YK0350000

CHEMICAL NAME :: s-Trioxane

CAS REGISTRY NUMBER :: 110-88-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C3-H6-O3

MOLECULAR WEIGHT :: 90.09

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 425 mg/kg

REFERENCE :: STBIBN Studia Biophysica. (Akademie-Verlag GmbH, Postfach 1233, Berlin DDR-1086, Ger. Dem. Rep.) V.1- 1966- Volume(issue)/page/year: 107,205,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1914 No. of Facilities: 138 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 5829 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H228-H335-H361d

[ Precautionary Statements ]:
P210-P261-P281

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
F:Flammable;Xn:Harmful;

[ Risk Phrases ]:
R11;R37;R63

[ Safety Phrases ]:
S36/37-S46

[ RIDADR ]:
UN 1325 4.1/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
YK0350000

[ Packaging Group ]:
III

[ Hazard Class ]:
4.1

[ HS Code ]:
2912600000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Genotoxic effects of dioxolane and trioxane in mice evaluated by the micronucleus test.

Toxicol. Lett. 21(3) , 349-52, (1984)

The possible genotoxic effects of dioxolane and trioxane were studied using the micronucleus test. Mice were given dioxolane and trioxane i.p. in two doses at 24-h intervals. Dioxolane at doses from 1...

Biodegradation of formaldehyde and its derivatives in industrial wastewater with methylotrophic yeast Hansenula polymorpha and with the yeast-bioaugmented activated sludge.

Biodegradation 13(2) , 91-9, (2002)

Methylotrophic yeast Hansenula polymorpha were shown to cooperate with activated sludge from biological wastewater treatment stations, enhancing substantially its potential to biodegrade formaldehyde ...

Reinvestigation of the Two-step Synthesis of Sevoflurane.

Iran. J. Pharm. Res. 14 , 733-8, (2015)

Improvements in the two-step synthesis of 1,1,1,3,3,3-hexafluoro-2- (fluoromehoxy)propane (Sevoflurane) that result in the product cost reduction, safety level enhancement and positive environmental i...