UNII:0W44HYL8T5
Names
[ CAS No. ]:
110-97-4
[ Name ]:
UNII:0W44HYL8T5
[Synonym ]:
DIPROPYL-2,2'-DIHYDROXYAMINE
1,1'-Iminodi(2-propanol)
diisopropanolamine
DIPA commercial grade
2-Propanol, 1,1'-iminobis-
1,1'-Imino-2-propanol
1,1'-Iminodipropan-2-ol
IMINODIPROPANOL
EINECS 203-820-9
UNII:0W44HYL8T5
1,1'-Azanediylbis(propan-2-ol)
Bis(2-hydroxypropyl)amine
Diisopropanolamin
1,1'-Iminobis[2-propanol]
DIPA NF
1,1'-Iminodi-2-propanol
DI-2-PROPANOLAMINE
MFCD00004531
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
254.4±15.0 °C at 760 mmHg
[ Melting Point ]:
42-45 °C(lit.)
[ Molecular Formula ]:
C6H15NO2
[ Molecular Weight ]:
133.189
[ Flash Point ]:
126.7±0.0 °C
[ Exact Mass ]:
133.110275
[ PSA ]:
52.49000
[ LogP ]:
-0.81
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.463
[ Water Solubility ]:
870 G/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UB6600000
- CHEMICAL NAME :
- 2-Propanol, 1,1'-iminodi-
- CAS REGISTRY NUMBER :
- 110-97-4
- BEILSTEIN REFERENCE NO. :
- 0605363
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C6-H15-N-O2
- MOLECULAR WEIGHT :
- 133.22
- WISWESSER LINE NOTATION :
- QY1&1M1YQ1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 5/21/1971
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 5/21/1971 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4765 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(7),46,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 96 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - beta-adrenergic blockage
- REFERENCE :
- AIMJA9 Ain Shams Medical Journal. (Ain Shams Clinical and Scientific Soc., c/o Ain Shams Univ. Hospital, Abbassia, Cairo, Egypt) V.1- 1950- Volume(issue)/page/year: 30,23,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(7),46,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 42 gm/kg/2W-C
- TOXIC EFFECTS :
- Musculoskeletal - other changes Related to Chronic Data - death
- REFERENCE :
- JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(1),53,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1242 No. of Facilities: 6081 (estimated) No. of Industries: 34 No. of Occupations: 44 No. of Employees: 73790 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1242 No. of Facilities: 1278 (estimated) No. of Industries: 26 No. of Occupations: 43 No. of Employees: 35237 (estimated) No. of Female Employees: 3439 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36
[ Safety Phrases ]:
S26
[ RIDADR ]:
3259
[ WGK Germany ]:
1
[ RTECS ]:
UB6600000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2922199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922199090
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Food Chem. Toxicol. 46(2) , 761-6, (2008)
Aminoalcohols differ in mammalian toxicity at least in part based upon their ability to alter the metabolism of phospholipids and to cause depletion of the essential nutrient choline in animals. This ...
Low expression of spindle checkpoint protein, Cenp-E, causes numerical chromosomal abnormalities in HepG-2 human hepatoma cells.Oncol. Lett. 10 , 2699-2704, (2016)
The aim of the present study was to investigate the expression, localization and role of centromere-associated protein E (Cenp-E) in hepatoma cells. The Cenp-E mRNA expression levels in the HepG-2 hum...
Triple allergic contact sensitivities due to ferbinac, crotamiton and diisopropanolamine.Contact Dermatitis 49(5) , 261-3, (2003)