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Dansyllysine

Names

[ CAS No. ]:
1101-84-4

[ Name ]:
Dansyllysine

[Synonym ]:
H-Lys(Dans)-OH
(2S)-2-amino-6-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]hexanoic acid
n6-{[5-(dimethylamino)naphthalen-1-yl]sulfonyl}-l-lysine
MFCD00069541
Nepsilon-Dansyl-L-lysine
N~6~-{[5-(DIMETHYLAMINO)-1-NAPHTHYL]SULFONYL}-L-LYSINE
dansyllysine
Dns-lysine
N(6)-dansyl-L-lysine

Biological Activity

[Description]:

Dansyllysine is a fluorescent compound that has significantly higher solubility in synthetic phosphatidylcholine (PC) membranes[1]

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.293g/cm3

[ Boiling Point ]:
594.1ºC at 760mmHg

[ Molecular Formula ]:
C18H25N3O4S

[ Molecular Weight ]:
379.47

[ Flash Point ]:
313.1ºC

[ Exact Mass ]:
379.15700

[ PSA ]:
121.11000

[ LogP ]:
3.93830

[ Vapour Pressure ]:
5.82E-15mmHg at 25°C

[ Index of Refraction ]:
1.619

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Determination of binding conformations of drugs to human serum albumin by transferred nuclear overhauser effect measurements and conformational analyses using high-temperature molecular dynamics calculations.

J. Pharm. Sci. 87 , 379-386, (1998)

The binding conformations of oxyphenbutazone (OXY), Nepsilon-dansyl-L-lysine (DNS-LYS), and furosemide (FU) to human serum albumin (HSA) have been investigated by molecular dynamics (MD) calculations ...

Cholesterol-free phospholipid domains may be the membrane feature selected by N epsilon-dansyl-L-lysine and merocyanine 540.

Biochem. Biophys. Res. Commun. 111(2) , 768-74, (1983)

We have used N epsilon-dansyl-L-lysine as a fluorescent membrane probe, to study cells taken from tissues concerned with immune function. There is a striking similarity between the staining selectivit...

The use of dansyl lysine to assess heat damage and thermotolerance of normal tissues.

Int. J. Radiat. Oncol. Biol. Phys. 14(5) , 983-8, (1988)

The fraction of cells excluding the fluorescent dye dansyl lysine has previously been shown to correlate well with heat-induced cell killing in a variety of mammalian cell lines and in murine tumors i...


More Articles


Related Compounds