AMG7703

Names

[ Name ]:
AMG7703

[Synonym ]:
AMG7703
(2S)-2-(4-Chlorophenyl)-3-methyl-N-(1,3-thiazol-2-yl)butanamide
MFCD21603909
Benzeneacetamide, 4-chloro-α-(1-methylethyl)-N-2-thiazolyl-, (αS)-

Biological Activity

[Description]:

AMG7703 (4-CMTB, AMG-7703) is an allosteric, selective agonist of FFAR2 (GPR43).

[References]

References 1. Hansen AH, et al. J Med Chem. 2018 Sep 24. doi: 10.1021/acs.jmedchem.8b00855. 2. Swaminath G, et al. FEBS Lett. 2010 Oct 8;584(19):4208-14. View Related Products by Target Free Fatty Acid Receptor (FFAR)

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C₁₄H₁₅ClN₂OS

[ Molecular Weight ]:
294.800

[ Exact Mass ]:
294.059357

[ LogP ]:
4.36

[ Index of Refraction ]:
1.620