2-(Butylamino)Ethanol

Names

[ CAS No. ]:
111-75-1

[ Name ]:
2-(Butylamino)Ethanol

[Synonym ]:
2-(BUTYLAMINO)ETHANOL
2-(BUTYLAMINO)-ETHANOL
N-Butylethanolamine
EINECS 203-904-5
MFCD00020570

Chemical & Physical Properties

[ Density]:
0.891 g/mL at 25 °C(lit.)

[ Boiling Point ]:
198-200 °C(lit.)

[ Melting Point ]:
28.94 °C(estimate)

[ Molecular Formula ]:
C₆H₁₅NO

[ Molecular Weight ]:
117.18900

[ Flash Point ]:
170 °F

[ Exact Mass ]:
117.11500

[ PSA ]:
32.26000

[ LogP ]:
0.75930

[ Vapour Pressure ]:
0.0875mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.444(lit.)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KK0175000

CHEMICAL NAME :: Ethanol, 2-butylamino-

CAS REGISTRY NUMBER :: 111-75-1

BEILSTEIN REFERENCE NO. :: 1732522

LAST UPDATED :: 199806

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H15-N-O

MOLECULAR WEIGHT :: 117.22

WISWESSER LINE NOTATION :: Q2M4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 840 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 12,486,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 7100 mg/kg

TOXIC EFFECTS :: Cardiac - change in rate Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - hypermotility, diarrhea

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,344,1966

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
22-34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 2735 8/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
KK0175000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

CRHR1 Receptor binding and lipophilicity of pyrrolopyrimidines, potential nonpeptide corticotropin-releasing hormone type 1 receptor antagonists.

Bioorg. Med. Chem. 10 , 175-183, (2002)

A series of compounds related to N-butyl-N-ethyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amine (1, antalarmin) have been prepared and evaluated for their CRHR1 binding af...

Selective toxicity of alkanolamines.

Antimicrob. Agents Chemother. 34(3) , 491-3, (1990)

The antimicrobial effects of diethanolamine, dimethylamino-methyl-propanol, and butylethanolamine are greatly enhanced at high pH. Their antimicrobial activities are closely correlated with their unch...

Sitzmann. Sitzmann ME, et al.

Propellants, Explos., Pyrotech. 31(2) , 124-30, (2006)