Hydroxypyruvic acid

Names

[ Name ]:
Hydroxypyruvic acid

[Synonym ]:
3-hydroxy-2-oxopropanoic acid
3-hydroxypyruvate
3-Hydroxypyruvic acid
OH-pyruvate
OH-pyr
hydroxy-pyruvic acid
3PY
hydroxypyruvate

Biological Activity

[Description]:

Hydroxypyruvic acid is an intermediate in the metabolism of Glycine, serine and threonine. It is a substrate for Serine--pyruvate aminotransferase and Glyoxylate reductase/hydroxypyruvate reductase.

[Related Catalog]:

Natural Products >> Acids and Aldehydes

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.546g/cm3

[ Boiling Point ]:
252.9ºC at 760mmHg

[ Molecular Formula ]:
C₃H₄O₄

[ Molecular Weight ]:
104.06100

[ Flash Point ]:
121ºC

[ Exact Mass ]:
104.01100

[ PSA ]:
74.60000

[ Vapour Pressure ]:
0.00292mmHg at 25°C

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C

[ Risk Phrases ]:
R22;R34

[ Safety Phrases ]:
S26;S45;S36/S37/S39

[ RIDADR ]:
UN3261 8/PG 3

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Highly sensitive GC/MS/MS method for quantitation of amino and nonamino organic acids.

Anal. Chem. 83(7) , 2705-11, (2011)

Metabolite profiling methods are important tools for measurement of metabolite pools in biological systems. While most metabolite profiling methods report relative intensities or depend on a few inter...

On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of "glycolate" units into ansamitocin and soraphen A.

J. Am. Chem. Soc. 128(44) , 14325-36, (2006)

Feeding experiments with isotope-labeled precursors rule out hydroxypyruvate and TCA cycle intermediates as the metabolic source of methoxymalonyl-ACP, the substrate for incorporation of "glycolate" u...

Oocyte and zygote ketoaldehyde utilisation.

Biochim. Biophys. Acta 1355(2) , 99-101, (1997)

Mouse oocytes and zygotes, when solubilised demonstrated that a range of ketoaldehydes could be utilised as substrates. Of the five ketoaldehydes investigated the overall substrate utilisation was hyd...