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Phe-Lys(Trt)-PAB

Names

[ CAS No. ]:
1116085-99-4

[ Name ]:
Phe-Lys(Trt)-PAB

Biological Activity

[Description]:

Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Others

[Target]

Cleavable

[References]

[1]. Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20(2):390-6.

Chemical & Physical Properties

[ Density]:
1.195±0.06 g/cm3(Predicted)

[ Boiling Point ]:
880.5±65.0 °C(Predicted)

[ Molecular Formula ]:
C₄₁H₄₄N₄O₃

[ Molecular Weight ]:
640.81

Related Compounds