N-Methylsuccinimide
Names
[ CAS No. ]:
1121-07-9
[ Name ]:
N-Methylsuccinimide
[Synonym ]:
1-Methyl-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-methyl-
MFCD00005517
1-Methylpyrrolidine-2,5-dione
N-Methylsuccinimide
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
234.0±0.0 °C at 760 mmHg
[ Melting Point ]:
61-70 °C(lit.)
[ Molecular Formula ]:
C5H7NO2
[ Molecular Weight ]:
113.115
[ Flash Point ]:
105.9±11.1 °C
[ Exact Mass ]:
113.047676
[ PSA ]:
37.38000
[ LogP ]:
-0.95
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.493
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S26-S36/37
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
UY1028650
[ HS Code ]:
2925190090
Synthetic Route
Customs
[ HS Code ]: 2925190090
[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Spectrosc. Lett. 29(4) , 739-47, (1996)
N-Methylsuccinimide in plasma and urine as a biomarker of exposure to N-methyl-2-pyrrolidone. Jönsson BAG and Åkesson B.
Int. Arch. Occup. Environ. Health 74(4) , 289-94, (2004)
Modeling the enolization of succinimide derivatives, a key step of racemization of aspartic acid residues: importance of a two-H2O mechanism.
Chem. Biodivers. 7(6) , 1349-56, (2010)
Racemization of aspartic acid residues in peptides and proteins is assumed to proceed via succinimide intermediates. An enolization of the succinimide intermediate is required for the racemization to ...