2,2'-Disulfanediyldianiline
Names
[ CAS No. ]:
1141-88-4
[ Name ]:
2,2'-Disulfanediyldianiline
[Synonym ]:
2-[(2-aminophenyl)disulfanyl]aniline
2,2'-Diaminodiphenyl disulphide
Di(2-aminophenyl) Disulfide
EINECS 214-529-1
2,2'-Diaminodiphenyl Disulfide
MFCD00007703
2,2'-Dithiodianiline
2-Aminophenyl Disulfide
2,2'-Disulfanediyldianiline
Benzenamine, 2,2'-dithiobis-
2,2'-Diamino diphenyl disulfide
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
398.0±27.0 °C at 760 mmHg
[ Melting Point ]:
91-92 °C(lit.)
[ Molecular Formula ]:
C12H12N2S2
[ Molecular Weight ]:
248.367
[ Flash Point ]:
194.5±23.7 °C
[ Exact Mass ]:
248.044189
[ PSA ]:
102.64000
[ LogP ]:
3.05
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.741
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BX9540000
- CHEMICAL NAME :
- Aniline, 2,2'-dithiobis-
- CAS REGISTRY NUMBER :
- 1141-88-4
- BEILSTEIN REFERENCE NO. :
- 0914032
- LAST UPDATED :
- 199703
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C12-H12-N2-S2
- MOLECULAR WEIGHT :
- 248.38
- WISWESSER LINE NOTATION :
- ZR BSSR BZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1005,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 178 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00263 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 434 mg/kg/7D-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - changes in iron
- REFERENCE :
- JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 5,414,1985
Safety Information
[ Symbol ]:
GHS05, GHS06, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H318-H410
[ Precautionary Statements ]:
P273-P280-P301 + P310-P305 + P351 + P338-P501
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R41
[ Safety Phrases ]:
S26-S39
[ RIDADR ]:
UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all
[ WGK Germany ]:
2
[ RTECS ]:
BX9540000
[ HS Code ]:
2930909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
J. Toxicol. Environ. Health A 7(1) , 69-81, (1981)
Guided by structure-activity relationships among carcinogenic aromatic amines, a sulfur-containing aromatic diamine was designed as a possible noncarcinogenic replacement for the resin hardener 4,4'-m...
Novel Tm(III) Membrane Sensor Based on 2,2'-Dianiline Disulfide and Its Application for the Fluoride Monitoring of Mouth Wash Preparations Ganjali, M.R., et al.Bull. Korean Chem. Soc. 27 (9) , 1418-1422, (2006)
A general and efficient synthesis of 2-phenylbenzothiazoles from diphenyl disulfides. Chang, Yi-Hua, et al.
Synth. Commun. 23 , 663-670, (1993)