Triisopropyl phosphite

Names

[ CAS No. ]:
116-17-6

[ Name ]:
Triisopropyl phosphite

[Synonym ]:
EINECS 204-130-0
tripropan-2-yl phosphite
Medronic acid impurity A
Triisopropyl phosphite
Phosphorous acid, triisopropyl ester (8CI)
Phosphorous acid, tris(1-methylethyl) ester
MFCD00008874

Chemical & Physical Properties

[ Density]:
0.914

[ Boiling Point ]:
181.4±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₂₁O₃P

[ Molecular Weight ]:
208.235

[ Flash Point ]:
67.8±0.0 °C

[ Exact Mass ]:
208.122833

[ PSA ]:
41.28000

[ LogP ]:
1.71

[ Vapour Pressure ]:
1.2±0.3 mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.411(lit.)

[ Water Solubility ]:
Insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TH2800000

CHEMICAL NAME :: Phosphorous acid, tris(1-methylethyl) ester

CAS REGISTRY NUMBER :: 116-17-6

BEILSTEIN REFERENCE NO. :: 1701528

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C9-H21-O3-P

MOLECULAR WEIGHT :: 208.27

WISWESSER LINE NOTATION :: 1Y1&OPOY1&1&OY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 167 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :: Insect - Drosophila melanogaster

DOSE/DURATION :: 50 mmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 28,405,1975

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315

[ Precautionary Statements ]:
Missing Phrase - N15.00950417

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R25;R38;R68

[ Safety Phrases ]:
S37-S46-S45-S36/37

[ RIDADR ]:
UN 3278 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
TH2800000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Surface characterization and platelet adhesion studies of plasma polymerized phosphite and its copolymers with dimethylsulfate.

Biomaterials 20(16) , 1439-47, (1999)

Due to its capability for using a wide variety of organic and inorganic compounds as the monomer source, including those which are not polymerizable by conventional methods, plasma polymerization has ...

Environmental change in Jiaozhou Bay recorded by nutrient components in sediments.

Mar. Pollut. Bull. 60(9) , 1591-9, (2010)

Inorganic or bulk organic chemical indicators, including organic carbon (OC), total nitrogen, organic nitrogen (ON), fixed ammonium (N(fix)), exchangeable ammonium, exchangeable nitrate, organic phosp...