Mebendazole-d3

Names

[ Name ]:
Mebendazole-d3

[Synonym ]:
Mebendazole-d3
Ovitelmin-d8
5-Benzoyl-2-benzimidazolecarbamic acid methyl-d3 ester
5-Benzoyl-2-benzimidazolecarbamic Acid-d8 Methyl Ester
Bantenol-d8
Mebex-d8
Pantelmin-d8
Mebenvet-d8
Noverme-d8

Biological Activity

[Description]:

Mebendazole-d3 is the deuterium labeled L-Methionine-34S[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₀D₃N₃O₃

[ Molecular Weight ]:
298.31

[ Exact Mass ]:
298.11500

[ PSA ]:
87.57000

[ LogP ]:
2.98580

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ Safety Phrases ]:
36

[ RIDADR ]:
NONH for all modes of transport