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Ublituximab

Names

[ CAS No. ]:
1174014-05-1

[ Name ]:
Ublituximab

Biological Activity

[Description]:

Ublituximab (LFB-R603; TG-1101; TGTX-1101) is a next-generation, type 1 chimeric monoclonal antibody targeting a unique epitope on the CD20 antigen. Ublituximab has anticancer effects[1].

[Related Catalog]:

Research Areas >> Cancer

[In Vitro]

Ublituximab 经过糖工程改造，具有含低岩藻糖的可结晶片段 (Fc) 区域，可增强抗体依赖性细胞毒性[1]。

[References]

[1]. Matthew Lunning, et al. Ublituximab and umbralisib in relapsed/refractory B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia. Blood. 2019 Nov 21;134(21):1811-1820.  

Chemical & Physical Properties

No Any Chemical & Physical Properties