Sodium larsucosterol

Names

[ Name ]:
Sodium larsucosterol

Biological Activity

[Description]:

Larsucosterol sodium is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis[1][2].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Ren S, Hylemon P, Zhang ZP, Rodriguez-Agudo D, Marques D, Li X, Zhou H, Gil G, Pandak WM. Identification of a novel sulfonated oxysterol, 5-cholesten-3beta,25-diol 3-sulfonate, in hepatocyte nuclei and mitochondria. J Lipid Res. 2006 May;47(5):1081-90. doi: 10.1194/jlr.M600019-JLR200. Epub 2006 Feb 27. PMID: 16505492.

[2]. Wang Y, Li X, Ren S. Cholesterol Metabolites 25-Hydroxycholesterol and 25-Hydroxycholesterol 3-Sulfate Are Potent Paired Regulators: From Discovery to Clinical Usage. Metabolites. 2020 Dec 25;11(1):9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₄₅NaO₅S

[ Molecular Weight ]:
504.70

[ Storage condition ]:
2-8°C