Lettowienolide

Names

[ Name ]:
Lettowienolide

[Synonym ]:
7-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-5-hydroxy-1-benzofuran-2(3H)-one
2(3H)-Benzofuranone, 7-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-5-hydroxy-

Biological Activity

[Description]:

Lettowienolide, a geranylbenzoquinonoid, exhibits mild in vitro activity against the Plasmodium falciparum malaria parasite (IC50~20 μg/mL)[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. John J Makangara, et al. Geranylbenzoquinonoids from Lettowianthus stellatus fruits. Nat Prod Res. 2010 May;24(8):710-7.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
453.2±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₂O₃

[ Molecular Weight ]:
286.366

[ Flash Point ]:
186.4±21.5 °C

[ Exact Mass ]:
286.156891

[ LogP ]:
4.61

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.568