Acetamide,N-(2-mercaptoethyl)-

Names

[ CAS No. ]:
1190-73-4

[ Name ]:
Acetamide,N-(2-mercaptoethyl)-

[Synonym ]:
N-(2-Mercaptoethyl)acetamide
N-(2-sulfanylethyl)acetamide
MFCD00037831

Chemical & Physical Properties

[ Density]:
1.121 g/mL at 25ºC(lit.)

[ Boiling Point ]:
138-140ºC7 mm Hg(lit.)

[ Melting Point ]:
6-7ºC(lit.)

[ Molecular Formula ]:
C₄H₉NOS

[ Molecular Weight ]:
119.18500

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
119.04000

[ PSA ]:
67.90000

[ LogP ]:
0.44320

[ Vapour Pressure ]:
0.00289mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.511(lit.)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AC4620000

CHEMICAL NAME :: Acetamide, N-(beta-mercaptoethyl)-

CAS REGISTRY NUMBER :: 1190-73-4

BEILSTEIN REFERENCE NO. :: 1743117

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C4-H9-N-O-S

MOLECULAR WEIGHT :: 119.20

WISWESSER LINE NOTATION :: SH2MV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RAREAE Radiation Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1954- Volume(issue)/page/year: 7,13,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 369 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 225,428,1955

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
AC4620000

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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4H-[1,2,5]Oxadiazolo[3,4-d]pyrimidine-5,7-dione 1-oxides (2) are conveniently prepared in high yields by the oxidative intramolecular cyclization of 6-amino-5-nitro-1H-pyrimidine-2,4-diones (1) employ...

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