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Vonafexor(PLX007,EYP-001)

Names

[ CAS No. ]:
1192171-69-9

[ Name ]:
Vonafexor(PLX007,EYP-001)

Biological Activity

[Description]:

Vonafexor (EYP001) is a selective FXR agonist with anti-HBV effects[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Metabolic Enzyme/Protease >> FXR

Signaling Pathways >> Anti-infection >> HBV

[References]

[1]. Joly S, et al. The selective FXR agonist EYP001 is well tolerated in healthy subjects and has additive anti-HBV effect with nucleoside analogues in HepaRG cells. J Hepatol 66(1):S690.

[2]. Fiorucci S,et al. Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH) [published online ahead of print, 2020 Jun 19]. Expert Opin Investig Drugs. 2020;1-10.

Chemical & Physical Properties

[ Density]:
1.604±0.06 g/cm3(Predicted)

[ Boiling Point ]:
680.5±65.0 °C(Predicted)

[ Molecular Formula ]:
C₁₉H₁₅Cl₃N₂O₅S

[ Molecular Weight ]:
489.76

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds