4,6-dichloropyrimidine
Names
[ CAS No. ]:
1193-21-1
[ Name ]:
4,6-dichloropyrimidine
[Synonym ]:
4,6-dichlorpyrimidin
Pyrimidine, 4,6-dichloro-
EINECS 214-770-2
4,6-Dichloro-1,3-diazine
Pyrimidine,4,6-dichloro
MFCD00006109
4,6-dichloropyrimidine
4,6-dichloro-pyrimidine
4,6-dichloropyrimidne
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
176.0±0.0 °C at 760 mmHg
[ Melting Point ]:
65-67 °C(lit.)
[ Molecular Formula ]:
C4H2Cl2N2
[ Molecular Weight ]:
148.978
[ Flash Point ]:
105.1±7.4 °C
[ Exact Mass ]:
147.959503
[ PSA ]:
25.78000
[ LogP ]:
1.29
[ Vapour Pressure ]:
1.5±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.559
[ Storage condition ]:
-20°C
MSDS
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C: Corrosive;
[ Risk Phrases ]:
R20/21/22;R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3263 8/PG 2
[ WGK Germany ]:
3
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
2942000000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Org. Chem. 75(3) , 741-7, (2010)
A number of N-substituted azacalix[4]pyrimidines were synthesized by two methods. While straightforward condensation reaction between 4,6-dichloropyrimidine and 4,6-bis(alkylamino)pyrimidines gave ide...
Design, synthesis, and evaluation of novel biarylpyrimidines: a new class of ligand for unusual nucleic acid structures.J. Med. Chem. 49 , 5187, (2006)
Biarylpyrimidines are characterized as selective ligands for higher-order nucleic acid structures. A concise and efficient synthesis has been devised incorporating Suzuki biaryl cross-coupling of diha...
Tetrahedron 62 , 10055, (2006)