4-Phenyl-2-pyrrolidinone
Names
[ CAS No. ]:
1198-97-6
[ Name ]:
4-Phenyl-2-pyrrolidinone
[Synonym ]:
4-phenylpyrrolidin-2-one
2-Pyrrolidinone, 4-phenyl-
4-Phenyl-2-pyrrolidinone
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
362.3±31.0 °C at 760 mmHg
[ Melting Point ]:
96 °C
[ Molecular Formula ]:
C10H11NO
[ Molecular Weight ]:
161.200
[ Flash Point ]:
212.4±9.8 °C
[ Exact Mass ]:
161.084061
[ PSA ]:
29.10000
[ LogP ]:
0.20
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.551
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UY5912000
- CHEMICAL NAME :
- 2-Pyrrolidinone, 4-phenyl-
- CAS REGISTRY NUMBER :
- 1198-97-6
- LAST UPDATED :
- 198608
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C10-H11-N-O
- MOLECULAR WEIGHT :
- 161.22
- WISWESSER LINE NOTATION :
- T5MVTJ DR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 325 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 23,733,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 352 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 14,776,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 352 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Behavioral - analgesia
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 44,22,1981
Safety Information
[ Hazard Codes ]:
Xi
[ HS Code ]:
2933790090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933790090
[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%