thrazarine

Names

[ CAS No. ]:
120128-14-5

[ Name ]:
thrazarine

[Synonym ]:
Thrazarine

Biological Activity

[Description]:

Thrazarine (FR 900840) is an oncology antibiotic that can be produced by Streptomyces coerulescens MH802-fF5. Thrazarine directly inhibits DNA synthesis and tumor cell growth. Thrazarine can specifically induce lysis of tumor cells co-cultured with non-activated macrophages. Thrazarine is used in cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Kameyama T, et al. Thrazarine, a new antitumor antibiotic. I. Taxonomy, fermentation, isolation and biological properties. J Antibiot (Tokyo). 1988 Nov;41(11):1561-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇H₁₁N₃O₅

[ Molecular Weight ]:
217.17900

[ Exact Mass ]:
217.07000

[ PSA ]:
143.99000