Ethyl 3-phenyl-2-oxiranecarboxylate

Names

[ CAS No. ]:
121-39-1

[ Name ]:
Ethyl 3-phenyl-2-oxiranecarboxylate

[Synonym ]:
ethyl3-phenyloxirane
ETHYL PHENYLGLYCIDATE FCC
FEMA 2454
3-phenyl-glycidicaciethylester
rac-3-phenyloxirane-2-carboxylic acid ethyl ester
trans-ethyl 2-phenylglycidate
ethyl 3-phenyl oxirane-2-carboxylate
3-phenyloxirane-2-carboxylic acid ethyl ester
MFCD00005123
Ethyl 3-Phenylglycidate
ethyl phenylglycidate
cis-ethyl-3-phenyloxirane-2-carboxylate
ETHYL A B-EPOXYHYDROCINNAMATE
3-Phenylglycidic Acid Ethyl Ester
ethyl3-phenyloxirane-2
ethyl3-phenyloxiranecarboxylate
ethyl 3-phenyl-2-oxiranecarboxylate
EINECS 204-467-3
Ethyl 3-Phenyloxiranecarboxylate
ethyl2,3-epoxy-3-phenylpropion

Chemical & Physical Properties

[ Density]:
1.102 g/mL at 25 °C(lit.)

[ Boiling Point ]:
96 °C0.5 mm Hg(lit.)

[ Molecular Formula ]:
C₁₁H₁₂O₃

[ Molecular Weight ]:
192.21100

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
192.07900

[ PSA ]:
38.83000

[ LogP ]:
1.68960

[ Vapour Pressure ]:
0.00184mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.518(lit.)

[ Storage condition ]:
0-6°C

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MB4970000

CHEMICAL NAME :: Glycidic acid, 3-phenyl-, ethyl ester

CAS REGISTRY NUMBER :: 121-39-1

BEILSTEIN REFERENCE NO. :: 0163394

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C11-H12-O3

MOLECULAR WEIGHT :: 192.23

WISWESSER LINE NOTATION :: T3OTJ BOV2 CR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 103 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 138,1,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4609 No. of Facilities: 18 (estimated) No. of Industries: 1 No. of Occupations: 13 No. of Employees: 3245 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4609 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1557 (estimated) No. of Female Employees: 276 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
MB4970000

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Epoxide hydrolase-catalyzed resolution of ethyl 3-phenylglycidate using whole cells of Pseudomonas sp.

Biotechnol. Lett. 25(24) , 2113-6, (2003)

A Pseudomonas sp. was isolated with enantioselective epoxide hydrolase activity to ethyl 3-phenylglycidate. Cells grown on sucrose and suspended in 10% (v/v) dimethyl formamide as co-solvent produced ...

Investigation of the mutagenicity of ethylphenylglycidate.

Mutat. Res. 138(1) , 1-8, (1984)

EPG and an in vitro digest of EPG by pepsin and pancreatin simulating mammalian digestion have been examined for genotoxicity in 4 mutagenicity tests employing different genetic endpoints. In the Salm...