4-Acetamidobenzenesulfonyl chloride

Names

[ CAS No. ]:
121-60-8

[ Name ]:
4-Acetamidobenzenesulfonyl chloride

[Synonym ]:
4-Acetamidobenzenesulfonyl Chloride
Sulfanilyl chloride, N-acetyl-
P-ACETAMIDOBENZENE SULFONYL CHLORIDE ASC
4-ACETAMIDOBENZENESULFONYLCHLORIDE
P-ACETYLSULPHANILYL CHLORIDE
ASC
UNII-LIX4M9AIVM
p-Acetamidophenylsulfonyl chloride
4-ACETAMINOBENZENESULFONYL CHLORIDE
N-Acetylsulfanilylchloride
p-Acetylaminobenzenesulfonyl chloride
EINECS 204-485-1
4-Acetamidophenylsulfonyl chloride
N-Acetylsulfanilyl chloride
N-Acetylsulfanyl Chloride
p-Acetaminobenzenesulfonyl chloride
4-(ACETYLAMINO)BENZENESULFONYL CHLORIDE
p-Acetamidobenzenesulfonyl chloride
4-Chlorosulfonylacetanilide
4-ACETAMIDOBENZENESULPHONYL CHLORIDE/N-ACETYLSULPHANILYL CHLORIDE] 121-60-8
N-ACETYLSULPHANILYL CHLORIDE
4-ACETAMIDEBENZENESULFONYL CHLORIDE
Acetanilide-p-sulfonyl chloride
4-ACETAMIDOBENZENE SULFONYL CHLORIDE
N-Acetyl sulfanilyl chloride
p-(Chlorosulfonyl)acetanilide
4-ACETAMIDOBENZENESULFONYL CHLORIDE FOR SYNTHESIS
4-ACETAMIDOBENZENESULPHONYL CHLORIDE
4-Acetamidobenzene-1-Sulfonyl Chloride
MFCD00007442
Benzenesulfonyl chloride, 4-(acetylamino)-

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
426.8±28.0 °C at 760 mmHg

[ Melting Point ]:
142-145 °C (dec.)(lit.)

[ Molecular Formula ]:
C₈H₈ClNO₃S

[ Molecular Weight ]:
233.672

[ Flash Point ]:
211.9±24.0 °C

[ Exact Mass ]:
232.991348

[ PSA ]:
71.62000

[ LogP ]:
1.55

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.586

[ Water Solubility ]:
SLIGHTLY SOLUBLE

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DB8837500

CHEMICAL NAME :: Benzenesulfonyl chloride, 4-(acetylamino)-

CAS REGISTRY NUMBER :: 121-60-8

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C8-H8-Cl-N-O3-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3200 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533583

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533583

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533583

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533583

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S28B

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
DB8837500

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29242995

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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