disodium,[3-(dimethylamino)-1-hydroxy-1-phosphonatopropyl]phosphonic acid
Names
[ CAS No. ]:
121368-58-9
[ Name ]:
disodium,[3-(dimethylamino)-1-hydroxy-1-phosphonatopropyl]phosphonic acid
[Synonym ]:
IG 8801
disodium [3-(dimethylamino)-1-hydroxy-1-phosphonatopropyl]phosphonic acid
Dimethyl APD
Disodium (3-(dimethylamino)-1-hydroxypropylidene)bisphosphate
UNII-G90M9V9GMQ
Phosphoric acid,(3-(dimethylamino)-1-hydroxypropylidene)bis-,disodium salt
Olpadronate sodium
Chemical & Physical Properties
[ Boiling Point ]:
590.1ºC at 760mmHg
[ Molecular Formula ]:
C5H13NNa2O7P2
[ Molecular Weight ]:
307.08600
[ Flash Point ]:
310.7ºC
[ Exact Mass ]:
306.99600
[ PSA ]:
163.81000
[ Vapour Pressure ]:
2.21E-16mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TC2509000
- CHEMICAL NAME :
- Phosphoric acid, (3-(dimethylamino)-1-hydroxypropylidene)bis-, disodium salt
- CAS REGISTRY NUMBER :
- 121368-58-9
- LAST UPDATED :
- 199603
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C5-H13-N-O7-P2.2Na
- MOLECULAR WEIGHT :
- 307.11
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 32400 mg/kg/27W-I
- TOXIC EFFECTS :
- Musculoskeletal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- BONEDL Bone. (Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.6- 1985- Volume(issue)/page/year: 16,285S,1995