BOC-L-phenylalanine-d5

Names

[ Name ]:
BOC-L-phenylalanine-d5

[Synonym ]:
N-Boc-L-phenyl-d5-alanine
Boc-Phe-OH-phenyl-d5
tert-Butoxycarbonyl-L-phenyl-d5-alanine
L-Phenyl-d5-alanine,N-t-Boc derivative

Biological Activity

[Description]:

BOC-L-phenylalanine-d5 is the deuterium labeled BOC-L-phenylalanine[1].

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.182g/cm3

[ Boiling Point ]:
426.6ºC at 760 mmHg

[ Melting Point ]:
85-87ºC(lit.)

[ Molecular Formula ]:
C₁₄H₁₄D₅NO₄

[ Molecular Weight ]:
270.34

[ Flash Point ]:
211.8ºC

[ Exact Mass ]:
270.16300

[ PSA ]:
75.63000

[ LogP ]:
2.59790

[ Vapour Pressure ]:
4.88E-08mmHg at 25°C

[ Index of Refraction ]:
1.528

Safety Information

[ WGK Germany ]:
3

BOC-L-phenylalanine-d5

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds