4'-Aminoacetanilide

Names

[ CAS No. ]:
122-80-5

[ Name ]:
4'-Aminoacetanilide

[Synonym ]:
EINECS 204-576-6
4‘-Aminoacetanilide
MFCD00050695
4-Acetamidoaniline
N-Acetyl-p-phenylenediamine
N-(4-aminophenyl)acetamide
N-Acetyl-1,4-phenylenediamine

Chemical & Physical Properties

[ Density]:
1.203 g/cm3

[ Boiling Point ]:
267 °C

[ Melting Point ]:
164-167 °C(lit.)

[ Molecular Formula ]:
C₈H₁₀N₂O

[ Molecular Weight ]:
150.17800

[ Flash Point ]:
195°C

[ Exact Mass ]:
150.07900

[ PSA ]:
55.12000

[ LogP ]:
1.88140

[ Vapour Pressure ]:
0.008mmHg at 25°C

[ Index of Refraction ]:
1.52

[ Water Solubility ]:
0.1-1 g/100 mL at 25 ºC

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AD8225000

CHEMICAL NAME :: Acetanilide, 4'-amino-

CAS REGISTRY NUMBER :: 122-80-5

BEILSTEIN REFERENCE NO. :: 0742888

LAST UPDATED :: 199712

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C8-H10-N2-O

MOLECULAR WEIGHT :: 150.20

WISWESSER LINE NOTATION :: ZR DMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 633 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81918 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 168 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81918 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 737 (estimated)

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H317-H319-H334

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S22-S26-S36/37-S39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
AD8225000

[ Hazard Class ]:
6.1

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Diazonium modification of porous graphitic carbon with catechol and amide groups for hydrophilic interaction and attenuated reversed phase liquid chromatography.

J. Chromatogr. A. 1422 , 186-93, (2015)

Porous graphitic carbon (PGC) is an increasingly popular and attractive phase for HPLC on account of its chemical and thermal stability, and its unique separation mechanism. However, native PGC is str...