Girard's reagent T

Names

[ CAS No. ]:
123-46-6

[ Name ]:
Girard's reagent T

[Synonym ]:
Carbazoylmethyltrimethylammonium chloride
(Carboxymethyl)trimethylammonium chloride, hydrazide
Girard
trimethylacetylhydrazide ammonium chloride
Ethanaminium, 2-hydrazinyl-N,N,N-trimethyl-2-oxo-, chloride (1:1)
Grard'sreagentT
Acethydrazide trimethylammonium chloride
Girard's reagent T
MFCD00012009
(carboxymethyl) trimethylammonium chloride hydrazide
GIRARD-REAGENT T
(Carboxymethyl)trimethylammonium chloride hydrazide
GIRARD'S T
GIRARD T
(Hydrazinocarbonylmethyl)trimethylammonium Chloride
2-Hydrazino-N,N,N-trimethyl-2-oxoethanaminium chloride
Trimethylacetohydrazideammonium Chloride
EINECS 204-629-3
girardtreagent
Betaine Hydrazide Hydrochloride
GIRARD'S T REAGEN T

Biological Activity

[Description]:

Girard’s reagent T is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Melting Point ]:
188-192 °C (dec.)(lit.)

[ Molecular Formula ]:
C₅H₁₄ClN₃O

[ Molecular Weight ]:
167.637

[ Exact Mass ]:
167.082535

[ PSA ]:
55.12000

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CP3150000

CHEMICAL NAME :: Ammonium, (carboxymethyl)trimethyl-, chloride, hydrazide

CAS REGISTRY NUMBER :: 123-46-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C5-H14-N3-O.Cl

MOLECULAR WEIGHT :: 167.67

WISWESSER LINE NOTATION :: ZMV1K1&1&1 &G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,25,1953

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F:Flammable;Xn:Harmful;

[ Risk Phrases ]:
R11;R20/22;R36/37/38;R44

[ Safety Phrases ]:
S22-S24/25-S36/37/39-S26-S16

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CP3150000

[ HS Code ]:
2928000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Derivatization with Girard reagent T combined with LC-MS/MS for the sensitive detection of 5-formyl-2'-deoxyuridine in cellular DNA.

Anal. Chem. 79(1) , 322-6, (2007)

Nucleoside 5-formyl-2'-deoxyuridine (FodU) is a major thymidine lesion generated by reactive oxygen species. In vitro and in vivo replication studies revealed that FodU can be mutagenic. A reliable an...

Girard derivatization for LC-MS/MS profiling of endogenous ecdysteroids in Drosophila.

J. Lipid Res. 54(8) , 2265-72, (2013)

Ecdysteroids are potent developmental regulators that control molting, reproduction, and stress response in arthropods. In developing larvae, picogram quantities of individual ecdysteroids and their c...

Derivatization of small oligosaccharides prior to analysis by matrix-assisted laser desorption/ionization using glycidyltrimethylammonium chloride and Girard's reagent T.

Rapid Commun. Mass Spectrom. 16(10) , 905-12, (2002)

In matrix-assisted laser desorption/ionization (MALDI) analyses of small oligosaccharides a very large increase in sensitivity (by a factor of 1000) may be obtained by introducing a quaternary ammoniu...