Compound 10

Names

[ Name ]:
Compound 10

[Synonym ]:
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid
GPR35 Agonist,Compound 10

Biological Activity

[Description]:

GPR35 agonist 3 is a synthetic GPR35 agonist with an EC50value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Research Areas >> Inflammation/Immunology

Research Areas >> Metabolic Disease

Research Areas >> Neurological Disease

[Target]

EC50: 1.4 μM (GPR35)[1]. Ki: 0.0508 μM (GPR35)[1]. IC50: 0.349 μM (GPR35)[1].

[In Vitro]

GPR35 agonist 3 shows GPR35 agonist potency with an EC50 value of 1.4 μM[1]. GPR35 agonist 3 has affinity and potency for GPR35 with values of 0.0508μM (Ki) and 0.349 μM (IC50)[1].

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₉NO₅S

[ Molecular Weight ]:
279.26900

[ Exact Mass ]:
279.02000

[ PSA ]:
121.49000

[ LogP ]:
1.74980

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport