H-Cys-Ser-Arg-Ala-Arg-Lys-Gln-Ala-Ala-Ser-Ile-Lys-Val-Ala-Val-Ser-Ala-Asp-Arg-OH trifluoroacetate salt

Names

[ Name ]:
H-Cys-Ser-Arg-Ala-Arg-Lys-Gln-Ala-Ala-Ser-Ile-Lys-Val-Ala-Val-Ser-Ala-Asp-Arg-OH trifluoroacetate salt

[Synonym ]:
Cys-Ser-Arg-Ala-Arg-Lys-Gln-Ala-Ala-Ser-Ile-Lys-Val-Ala-Val-Ser-Ala-Asp-Arg

Biological Activity

[Description]:

PA22-2 (free acid) (Cys-Laminin A chain 2091-2108) is a peptide that supports neurite outgrowth and stimulates neuronal-like process formation. PA22-2 (free acid) can be used to culture human adenoid cystic carcinoma cells, and in the preparation of peptide-functionalized supported phospholipid bilayers[1][2][3].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Yung-Chih Kuo, et al. Inverted colloidal crystal scaffolds with induced pluripotent stem cells for nerve tissue engineering. Colloids Surf B Biointerfaces. 2013 Feb 1:102:789-94.

[2]. D Thid, et al. Supported phospholipid bilayers as a platform for neural progenitor cell culture.J Biomed Mater Res A. 2008 Mar 15;84(4):940-53.

[3]. Ahu Arslan Yildiz, et al. Cell-free synthesis of cytochrome bo(3) ubiquinol oxidase in artificial membranes. Anal Biochem. 2012 Apr 1;423(1):39-45.

Chemical & Physical Properties

[ Molecular Formula ]:
C₈₂H₁₄₉N₃₁O₂₆S

[ Molecular Weight ]:
2017.32000

[ Exact Mass ]:
2016.10000

[ PSA ]:
1004.74000

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Laminin A chain synthetic peptide which supports neurite outgrowth.

Biochem. Biophys. Res. Commun. 162 , 821, (1989)

Neurons from peripheral and central nervous tissue as well as from established cell lines respond to low concentrations of laminin with rapid extension of axon-like processes. Two sites on laminin hav...