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Kazinol U

Names

[ CAS No. ]:
1238116-48-7

[ Name ]:
Kazinol U

[Synonym ]:
4-[(2R)-7-Hydroxy-3,4-dihydro-2H-chromen-2-yl]-3-(3-methyl-2-buten-1-yl)-1,2-benzenediol
1,2-Benzenediol, 4-[(2R)-3,4-dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)-

Biological Activity

[Description]:

Kazinol U inhibits melanogenesis through the inhibition of tyrosinase-related proteins via AMPK activation[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> AMPK
Research Areas >> Others
Signaling Pathways >> PI3K/Akt/mTOR >> AMPK

[References]

[1]. Lim J, et al. Kazinol U inhibits melanogenesis through the inhibition of tyrosinase-related proteins via AMP kinase activation. Br J Pharmacol. 2019;176(5):737-750.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
538.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H22O4

[ Molecular Weight ]:
326.39

[ Flash Point ]:
279.7±30.1 °C

[ Exact Mass ]:
326.151794

[ PSA ]:
69.92000

[ LogP ]:
4.57

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.631

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds