[(1S,3R,4S,4aS,7S,8S,8aS)-8-[2-[(2R,4R)-4-[tert-butyl(dimethyl)silyl]oxy-6-oxooxan-2-yl]ethyl]-4-chloro-4a-hydroxy-3,7-dimethyl-2,3,4,7,8,8a-hexahydro-1H-naphthalen-1-yl] 2,2-dimethylbutanoate

Names

[ CAS No. ]:
123852-10-8

[ Name ]:
[(1S,3R,4S,4aS,7S,8S,8aS)-8-[2-[(2R,4R)-4-[tert-butyl(dimethyl)silyl]oxy-6-oxooxan-2-yl]ethyl]-4-chloro-4a-hydroxy-3,7-dimethyl-2,3,4,7,8,8a-hexahydro-1H-naphthalen-1-yl] 2,2-dimethylbutanoate

[Synonym ]:
4-tert-Butyldimethylsilyl-5'-chloro-4a'-hydroxy Simvastatin
2,2-Dimethylbutanoic Acid [1S-[1|A,3|A,4|A,4a|A,7|A,8|A(2S*,4S*)]]-4-Chloro-8-[2-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3,7-dimethyl-1-naphthalenyl Ester

Chemical & Physical Properties

[ Density]:
1.09g/cm3

[ Boiling Point ]:
618.9ºC at 760 mmHg

[ Molecular Formula ]:
C31H53ClO6Si

[ Molecular Weight ]:
585.28700

[ Flash Point ]:
328.1ºC

[ Exact Mass ]:
584.33000

[ PSA ]:
82.06000

[ LogP ]:
7.02720

[ Vapour Pressure ]:
6.55E-18mmHg at 25°C

[ Index of Refraction ]:
1.51

Synthetic Route

Precursor & DownStream


Related Compounds