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9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine

Names

[ CAS No. ]:
124775-29-7

[ Name ]:
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine

[Synonym ]:
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purine
9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-
MFCD28125312

Biological Activity

[Description]:

9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
544.8±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C10H11FN4O3

[ Molecular Weight ]:
254.22

[ Flash Point ]:
283.3±32.9 °C

[ Exact Mass ]:
254.081512

[ LogP ]:
-0.20

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.772

Related Compounds