3β,5α,6β-Trihydroxycholestane

Names

[ Name ]:
3β,5α,6β-Trihydroxycholestane

[Synonym ]:
5α-Cholestane-3β,5,6β-triol (8CI)
Cholestane-3beta,5alpha,6beta-triol
(3β,5α,6β)-Cholestane-3,5,6-triol
Cholesta-3beta,5alpha,6beta-triol
3β,5α,6β-Trihydroxycholestane
5alpha,6beta-Dihydroxycholestanol
5α-Cholestane-3β,5,6β-triol
cholestanetriol
(3S,5R,6R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,5,6-triol
3beta,5alpha,6beta-Trihydroxycholestane
5alpha-cholestane-3beta,5,6beta-triol
Cholestane-3,5,6-triol, (3β,5α,6β)-
3beta,5alpha,6beta-Cholestanetriol

Biological Activity

[Description]:

3β,5α,6β-Trihydroxycholestane is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
515.7±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₇H₄₈O₃

[ Molecular Weight ]:
420.668

[ Flash Point ]:
212.5±21.9 °C

[ Exact Mass ]:
420.360352

[ PSA ]:
60.69000

[ LogP ]:
7.73

[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C

[ Index of Refraction ]:
1.538

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FZ6275000

CHEMICAL NAME :: Cholestane-3-beta,5-alpha,6-beta-triol

CAS REGISTRY NUMBER :: 1253-84-5

LAST UPDATED :: 199610

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C27-H48-O3

MOLECULAR WEIGHT :: 420.75

WISWESSER LINE NOTATION :: L E5 B666TJ A1 E1 FY1&3Y1&1 LQ MQ OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 130 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8400 mg/kg/2W-C

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg/2D-I

TOXIC EFFECTS :: Endocrine - changes in spleen weight

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 12 umol/L

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 24,1103,1986

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
20/21/22-68/20/21/22

[ Safety Phrases ]:
36