KNT-127
Names
[ CAS No. ]:
1256921-89-7
[ Name ]:
KNT-127
Biological Activity
[Description]:
A potent, selectove δ-opioid receptor agonist with Ki of 0.16 nM, dispalys 133.5-fold and 960.5-fold selectivity over μOR and κOR respectively; significantly decreases the duration of immobility and increased the duration of swimming without influencing spontaneous locomotor activity in mice (1mg/kg, s.c.).
[References]
References 1. Nagase H, et al. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6302-5. 2. Saitoh A, et al. Behav Brain Res. 2011 Oct 1;223(2):271-9. 3. Tanahashi S, et al. Neuropharmacology. 2012 Apr;62(5-6):2057-67. View Related Products by Target Opioid Receptor
Chemical & Physical Properties
[ Molecular Formula ]:
C24H24N2O2
[ Molecular Weight ]:
372.468