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TC-E 5006

Names

[ CAS No. ]:
1257395-14-4

[ Name ]:
TC-E 5006

Biological Activity

[Description]:

(Rac)-BIIB042 (Compound 10) is an modulator of γ-Secretase. (Rac)-BIIB042 reduces Amyloid-β 42 level with an EC50 value of 0.39 µM. (Rac)-BIIB042 can be used for the study of Alzheimer's disease[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Peng H, et al. Discovery of BIIB042, a Potent, Selective, and Orally Bioavailable γ-Secretase Modulator. ACS Med Chem Lett. 2011 Aug 5;2(10):786-91.  

Chemical & Physical Properties

[ Molecular Formula ]:
C29H29F4NO2

[ Molecular Weight ]:
499.54000

[ Exact Mass ]:
499.21300

[ PSA ]:
40.54000

[ LogP ]:
7.45880

Related Compounds