Pyruvic acid

Names

[ CAS No. ]:
127-17-3

[ Name ]:
Pyruvic acid

[Synonym ]:
FEMA 2970
2-Ketopropionic Acid
ACETYLFORMIC ACID
2-oxo-propanoicaci
2-Oxopropanoic acid
2-Oxopropionic Acid
pyruvic
CH3COCOOH
PYRUVIC-ACID
Pyruvic Acid
PYRORACEMIC ACID
PYRUVIC ACID pure
EINECS 204-824-3
ACID PYRUVATE
2-ketopropanoic acid
MFCD00002585

Biological Activity

[Description]:

Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

[Related Catalog]:

Natural Products >> Acids and Aldehydes

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Kładna A, et al. Reactivity of pyruvic acid and its derivatives towards reactive oxygen species. Luminescence. 2015 Nov;30(7):1153-8.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
165.0±0.0 °C at 760 mmHg

[ Melting Point ]:
11-12 °C(lit.)

[ Molecular Formula ]:
C₃H₄O₃

[ Molecular Weight ]:
88.062

[ Flash Point ]:
54.3±15.2 °C

[ Exact Mass ]:
88.016045

[ PSA ]:
54.37000

[ LogP ]:
-1.24

[ Vapour Pressure ]:
1.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.417

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases. Refrigerate.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UZ0829800

CHEMICAL NAME :: Pyruvic acid

CAS REGISTRY NUMBER :: 127-17-3

BEILSTEIN REFERENCE NO. :: 0506211

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C3-H4-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3533 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 81,1225,1961 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3953 No. of Facilities: 68 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 1014 (estimated) No. of Female Employees: 636 (estimated)

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S25-S27

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
UZ0829800

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29335995

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 29335995

Articles

Analysis of by-product formation and sugar monomerization in sugarcane bagasse pretreated at pilot plant scale: differences between autohydrolysis, alkaline and acid pretreatment.

Bioresour. Technol. 181 , 114-23, (2015)

Sugarcane bagasse is an interesting feedstock for the biobased economy since a large fraction is polymerized sugars. Autohydrolysis, alkaline and acid pretreatment conditions combined with enzyme hydr...

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Concentrations of organic acids in cerebrospinal fluid (CSF) appear to be directly dependent upon their rate of production in the brain. There is evidence that the net release of short-chain monocarbo...