4'-(pyrimidin-2-ylsulphamoyl)acetanilide

Names

[ CAS No. ]:
127-74-2

[ Name ]:
4'-(pyrimidin-2-ylsulphamoyl)acetanilide

[Synonym ]:
4N-Acetylsulfadiazine
EINECS 204-862-0
N-Acetyl Sulfadiazine
4'-(pyrimidin-2-ylsulphamoyl)acetanilide
N-[4-[(2-Pyrimidinylamino)sulfonyl]phenyl]acetamide
4-acetylamino-N-pyrimidin-2-yl-benzenesulfonamide
4'-(pyrimidin-2-ylsulfamoyl)acetanilide
4'-(2-Pyrimidinylsulfamoyl)acetanilide
N-Acetyl-sulfanilsaeure-pyrimidin-2-ylamid
N(4)-acetylsulfadiazine
2-[(p-Acetamidophenyl)sulfonamido]pyrimidine
N4-Acetylsulfadiazin
Acetylsulfadiazine

Chemical & Physical Properties

[ Density]:
1.475g/cm3

[ Melting Point ]:
260-262?C

[ Molecular Formula ]:
C₁₂H₁₂N₄O₃S

[ Molecular Weight ]:
292.31400

[ Exact Mass ]:
292.06300

[ PSA ]:
109.43000

[ LogP ]:
2.46260

[ Index of Refraction ]:
1.653

[ Storage condition ]:
Refrigerator

Safety Information

[ HS Code ]:
2935009090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

A conceptual model describing the fate of sulfadiazine and its metabolites observed in manure-amended soils.

Chemosphere 77(6) , 720-6, (2009)

Sulfadiazine (SDZ) belongs to the chemical class of sulfonamides, one of the most important groups of antibiotics applied in animal husbandry in Europe. These antibiotics end up in the soil after manu...

Determination of sulfadiazine and N4-acetylsulfadiazine in biological fluids by liquid chromatography on silica gel with an aqueous buffer as mobile phase.

J. Pharm. Sci. 71(10) , 1142-5, (1982)

Sulfadiazine and N4-acetylsulfadiazine were determined in biological fluids by the direct injection (plasma after protein precipitation and urine after dilution 100 times) of 20 microliters on a silic...

New simple liquid chromatographic method for the determination of trimethoprim, sulfadiazine and N4-acetylsulfadiazine in plasma of broilers.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 769(2) , 253-9, (2002)

A new method for simultaneous quantification of trimethoprim, sulfadiazine and N4-acetylsulfadiazine in plasma of broilers at levels down to 13-16 ng/ml has been developed. Samples were deproteinized ...