S(-)-5-FLUORO-8-HYDROXY-2-DIPROPYLAMINO-1,2,3,4-TETRAHYDRONAPHTHALENE HYDROCHLORIDE
Names
[ CAS No. ]:
127126-22-1
[ Name ]:
S(-)-5-FLUORO-8-HYDROXY-2-DIPROPYLAMINO-1,2,3,4-TETRAHYDRONAPHTHALENE HYDROCHLORIDE
[Synonym ]:
unii-1t7773jh5n
Chemical & Physical Properties
[ Boiling Point ]:
382ºC at 760 mmHg
[ Molecular Formula ]:
C16H25ClFNO
[ Molecular Weight ]:
301.82700
[ Flash Point ]:
184.8ºC
[ Exact Mass ]:
301.16100
[ PSA ]:
23.47000
[ LogP ]:
4.31260
[ Vapour Pressure ]:
2.22E-06mmHg at 25°C
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Articles
Eur. Neuropsychopharmacol. 9 , 15-19, (1999)
The receptor-mediated control of brain monoamine synthesis was used to examine the in vivo intrinsic efficacy of the 5-HT1A receptor antagonists NAD-299, S(-)-UH-301 and WAY-100,635. The rate of monoa...
Pharmacology of the novel 5-hydroxytryptamine1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: inhibition of (R)-8-hydroxy-2-(dipropylamino)tetralin-induced effects.J. Pharmacol. Exp. Ther. 258 , 58, (1991)
The selective 5-hydroxytryptamine (5-HT1A) receptor agonist 8-hydroxy-2-(dipropylamino)tetralin (8-OH-DPAT) induces a large number of pharmacological effects. In the present study we demonstrate that ...
The 5-HT1A receptor selective ligands, (R)-8-OH-DPAT and (S)-UH-301, differentially affect the activity of midbrain dopamine neurons.Naunyn Schmiedebergs Arch. Pharmacol. 347 , 353-362, (1993)
The effects of the selective 5-HT1A receptor agonist (R)-8-hydroxy-2(di-n-propylamino)tetralin [(R)-8-OH-DPAT] and the novel 5-HT1A antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)-tetralin [(S)-UH...