(2-Hydroxypropyl)-γ-cyclodextrin

Names

[ Name ]:
(2-Hydroxypropyl)-γ-cyclodextrin

[Synonym ]:
2-fluoro-4-methyl-1-nitrobenzene
MFCD00007053
5,10,25-Tris(hydroxymethyl)-15,20,30,35,40-pentakis[(2-hydroxypropoxy)methyl]-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.2.2.2.2.2.2 .2]hexapentacontane-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecol (non-preferred name)
EINECS 207-166-5
hydrxypropyl- gamma-cyclodextrin

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
97-98ºC3 mm Hg(lit.)

[ Melting Point ]:
52-55ºC(lit.)

[ Molecular Formula ]:
C₇H₆FNO₂

[ Molecular Weight ]:
1587.521

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
1586.631958

[ PSA ]:
45.82000

[ LogP ]:
-8.72

[ Index of Refraction ]:
1.557

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

When administered to rats in a cold environment, 3,4-methylenedioxymethamphetamine reduces brown adipose tissue thermogenesis and increases tail blood flow: Effects of pretreatment with 5-HT1A and dopamine D2 antagonists

Neuroscience 154 , 1619-26, (2008)

When given in a warm environment MDMA (3,4-methylenedioxymethamphetamine, ecstasy) causes hyperthermia by increasing interscapular brown adipose tissue (iBAT) heat production and decreasing heat loss ...

Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking.

Eur. J. Neurosci. 30 , 493-503, (2009)

The orexin/hypocretin system has recently been implicated in reward-processing and addiction. We examined the involvement of the orexin system in cue-induced reinstatement of extinguished cocaine-seek...

The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73.

Cell Death Differ. 14 , 743-51, (2007)

Upon DNA damage signaling, p73, a member of the p53 tumor suppressor family, accumulates to support transcription of downstream apoptotic genes. p73 interacts with Yes-associated protein 1 (Yap1) thro...