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BMVC-8C3O

Names

[ CAS No. ]:
1301708-12-2

[ Name ]:
BMVC-8C3O

Biological Activity

[Description]:

BMVC-8C3O is a DNA G-quadruplexe (G4) ligand which can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

BMVC-8C3O induces topological conversion of Tel23 from a hybrid-I G4 to a parallel G4 in K+solution[1]. BMVC-8C3O binding can induce topological changes of different non-parallel human telomeric G4s into the same parallel topology[1].

[References]

[1]. Wang ZF, et al. A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes. Nucleic Acids Res. 2016 May 5;44(8):3958-68.

Chemical & Physical Properties

[ Molecular Formula ]:
C42H53I3N4O3

[ Molecular Weight ]:
1042.61

[ Storage condition ]:
-20°C

Related Compounds