MC2050 HCl

Names

[ Name ]:
MC2050 HCl

Biological Activity

[Description]:

MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₃Cl₂N₅Os

[ Molecular Weight ]:
440.387

Related Compounds

MDL72274 HCl
EPZ020411 HCl
Meclizine HCl
Epinastin HCl
TRC051384 HCl
ProCH3, HCl Ethanone, 1-(2-pyrrolidinyl)-, (S)- (9CI) Hydrochloride
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