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Cirsimarin

Names

[ CAS No. ]:
13020-19-4

[ Name ]:
Cirsimarin

[Synonym ]:
5-hydroxy-6,6-dimethoxy-5-methyl-1-phenyl-3-hexanone
3-Hexanone,5-hydroxy-6,6-dimethoxy-5-methyl-1-phenyl
5-hydroxy-6,7-dimethoxyflavone-4'-glucoside

Biological Activity

[Description]:

Cirsimarin is a potent antilipogenic flavonoid isolated from Microtea debilis. Cirsimarin exerts potent antilipogenic effect and decreases adipose tissue deposition in mice. The lipolytic activity of Cirsimarin resulting from both its antagonist activity on adenosin A1 receptor and its inhibitory effect on phosphodiesterase[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Research Areas >> Metabolic Disease

[Target]

Phosphodiesterase[1]; Adenosin A1 receptor[1]


[References]

[1]. Zarrouki B, et al. Cirsimarin, a potent antilipogenic flavonoid, decreases fat deposition in mice intra-abdominal adipose tissue. Int J Obes (Lond). 2010 Nov;34(11):1566-75.

Chemical & Physical Properties

[ Density]:
1.523g/cm3

[ Boiling Point ]:
767.1ºC at 760 mmHg

[ Molecular Formula ]:
C23H24O11

[ Molecular Weight ]:
476.43000

[ Flash Point ]:
265.8ºC

[ Exact Mass ]:
476.13200

[ PSA ]:
168.28000

[ LogP ]:
0.36150

[ Vapour Pressure ]:
9.47E-25mmHg at 25°C

[ Index of Refraction ]:
1.657

Related Compounds