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(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one

Names

[ CAS No. ]:
130931-83-8

[ Name ]:
(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one

[Synonym ]:
2-Azabicyclo[2.2.1]hept-5-en-3-one
(1S,4R)-(+)-2-azabicyclo<2.2.1>hept-5-en-3-one
MFCD00211275
(1R)-(-)-2-azabicyclo[2.2.1]hept-5-en-3-one
EINECS 421-830-3
T55 A CMV FUTJ
4-Amino-2-cyclopentene-1-carboxylic acid lactam
(1R),(5S)-(-)-2-azabicyclo[2.2.1]hept-5-en-3-one
(+)-VINCE'S LACTAM
2-Azabicyclo[2.2.1]hept-5-en-3-one, (1S,4R)-
(1S)-(+)-2-AZABICYCLO[2.2.1]HEPT-5-EN-3-ONE
Vince lactam
2-Azabicyclo[2.2.1]hept-5-en-3-one,(1S,4R)
(+)-Vince lactam
(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one
(+)-2-AZABICYCLO[2,2,1]HEPT-5-EN-3-ONE

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
319.3±0.0 °C at 760 mmHg

[ Melting Point ]:
92-100ºC

[ Molecular Formula ]:
C6H7NO

[ Molecular Weight ]:
109.126

[ Flash Point ]:
167.1±9.8 °C

[ Exact Mass ]:
109.052765

[ PSA ]:
29.10000

[ LogP ]:
-1.22

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.546

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933790090

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides.

J. Med. Chem. 33 , 17, (1990)

(+-)-cis-[4-[(2,5-Diamino-6-chloropyrimidinyl)amino]-2- cyclopentenyl]carbinol (5a) was synthesized from 2-amino-4,6-dichloropyrimidine and cis-4-(hydroxymethyl)cyclopentenylamine (2a) by subsequent p...

Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases.

Biochem. Biophys. Res. Commun. 161 , 393, (1989)

Carbocylic 2',3'-didehydro-2',3'-dideoxyguanosine (Carbovir; NSC 614846) is an antiretroviral agent which may be useful in the treatment of AIDS. We have synthesized the 5'-triphosphate of Carbovir an...

Evans, C.T. et al.

J. Chem. Soc. Perkin Trans. I , 589, (1992)


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