2-Methyl-5-nitroanisole

Names

[ Name ]:
2-Methyl-5-nitroanisole

[Synonym ]:
1-Methoxy-2-methyl-5-nitrobenzene
2-Methyl-5-nitroanisole
Methyl 2-methyl-5-nitrophenyl ether
2-Methoxy-4-nitrotoluene
Anisole, 2-methyl-5-nitro-
Benzene, 2-methoxy-1-methyl-4-nitro-
EINECS 236-048-6
2-Methoxy-1-methyl-4-nitrobenzene
MFCD00043912

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
281.2±20.0 °C at 760 mmHg

[ Melting Point ]:
69-71 °C(lit.)

[ Molecular Formula ]:
C₈H₉NO₃

[ Molecular Weight ]:
167.162

[ Flash Point ]:
135.5±23.8 °C

[ Exact Mass ]:
167.058243

[ PSA ]:
55.05000

[ LogP ]:
2.63

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.538

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2909309090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Oxidation of substituted 4-fluorobenzaldehydes: application to the no-carrier-added syntheses of 4-[18F]fluoroguaiacol and 4-[18F]fluorocatechol.

Int. J. Rad. Appl. Instrum. A. 42(7) , 673-81, (1991)

The synthesis of 4-[18F]fluoroguaiacol (4-[18F]fluoro-2-methoxyphenol) has been achieved in no-carrier-added form starting from 2-methoxy-4-nitrobenzaldehyde, using nucleophilic aromatic substitution ...

Anodic oxidations. VII. Nuclear cyanation of methylanisoles. Yoshida K, et al.

J. Org. Chem. 40(1) , 63-66, (1975)