3-Aminopropylphosphonic acid

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
343.0±44.0 °C at 760 mmHg

[ Melting Point ]:
290-294ºC

[ Molecular Formula ]:
C₃H₁₀NO₃P

[ Molecular Weight ]:
139.090

[ Flash Point ]:
161.2±28.4 °C

[ Exact Mass ]:
139.039825

[ PSA ]:
93.36000

[ LogP ]:
-2.38

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.495

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
soluble

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2931900090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Activation of GABA B receptors in the anterior pituitary inhibits prolactin and luteinizing hormone secretion.

Neuroendocrinology 56 , 687, (1992)

Previous work from our laboratory showed that baclofen could lower serum prolactin (PRL) levels acting at the central nervous system. The present experiments were designed to evaluate whether the gamm...

Differential effects of phosphonic analogues of GABA on GABA(B) autoreceptors in rat neocortical slices.

Naunyn Schmiedebergs Arch. Pharmacol. 357 , 408-412, (1998)

The effects of five phosphonic derivatives of GABA on the release of [3H]-GABA from rat neocortical slices, preloaded with [3H]-GABA, were investigated. Phaclofen and 4-aminobutylphosphonic acid (4-AB...

Evidence for pharmacologically distinct subsets of GABAB receptors.

Brain Res. Bull. 21 , 439-443, (1988)

Activation of GABAB receptors augments neurotransmitter-stimulated cyclic AMP accumulation while inhibiting forskolin-mediated second messenger production. Previous studies have revealed that GABAB re...

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