T808

Names

[ CAS No. ]:
1320211-61-7

[ Name ]:
T808

[Synonym ]:
T-808
AVI-680
Pyrimido(1,2-a)benzimidazole,2-(4-(2-fluoroethyl)-1-piperidinyl)
UNII-58FK27W8WL

Biological Activity

[Description]:

T808 is a tau-selective Alzheimer’s PET ligand. T808 is a type of imaging agent used in positron emission tomography (PET) scans. It is a radiotracer that is used to help visualize certain areas of the body, such as the brain, in order to diagnose and monitor various medical conditions[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Liu L, et al. [11C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins. J Med Chem. 2021 Aug 26;64(16):12003-12021.  

Chemical & Physical Properties

[ Molecular Formula ]:
C17H19FN4

[ Molecular Weight ]:
298.35800

[ Exact Mass ]:
298.15900

[ PSA ]:
33.43000

[ LogP ]:
3.52350

Related Compounds