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(R)-3-Hydroxybutanoic acid-13c sodium

Names

[ CAS No. ]:
13291-89-9

[ Name ]:
(R)-3-Hydroxybutanoic acid-13c sodium

[Synonym ]:
Propionic acid-1,2-13C2 sodium salt
Sodium propionate-1,2-13C2
acetic-2-13C acid sodium salt
13C-labeled sodium acetate
sodium <1,2-13C2>propionate
MFCD00037668

Biological Activity

[Description]:

(R)-3-Hydroxybutanoic acid-13C (sodium) is the 13C labeled (R)-3-Hydroxybutanoic acid sodium[1]. (R)-3-Hydroxybutanoic acid sodium ((R)-3-Hydroxybutyric acid) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[2][3].

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Ide T. Enzymatic-HPLC method to analyze D-3-hydroxybutyric acid in rat serum. Biosci Biotechnol Biochem. 2010;74(8):1578-82.  

[3]. Mateusz Biernacki, et al. Production of (R)-3-hydroxybutyric acid by Arxula adeninivorans. AMB Express. 2017 Dec7(1):4.  

Chemical & Physical Properties

[ Melting Point ]:
>300ºC (dec.)(lit.)

[ Molecular Formula ]:
C2H3NaO2

[ Molecular Weight ]:
83.02640

[ Exact Mass ]:
83.00640

[ PSA ]:
40.13000

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

DownStream

Related Compounds