Pentachlorothiophenol
Names
[ CAS No. ]:
133-49-3
[ Name ]:
Pentachlorothiophenol
[Synonym ]:
Pentachlorothiophenol
2,3,4,5,6-pentachlorobenzenethiol
Benzenethiol, 2,3,4,5,6-pentachloro-
EINECS 205-107-8
Pentachlorobenzenethiol
MFCD00059146
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
351.3±37.0 °C at 760 mmHg
[ Melting Point ]:
223-227 °C(lit.)
[ Molecular Formula ]:
C6HCl5S
[ Molecular Weight ]:
282.402
[ Flash Point ]:
144.6±25.9 °C
[ Exact Mass ]:
279.824158
[ PSA ]:
38.80000
[ LogP ]:
5.43
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.648
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DC1925000
- CHEMICAL NAME :
- Benzenethiol, pentachloro-
- CAS REGISTRY NUMBER :
- 133-49-3
- BEILSTEIN REFERENCE NO. :
- 1108638
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C6-H-Cl5-S
- MOLECULAR WEIGHT :
- 282.38
- WISWESSER LINE NOTATION :
- SHR BG CG DG EG FG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,989,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81922 No. of Facilities: 61 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 769 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81922 No. of Facilities: 1259 (estimated) No. of Industries: 6 No. of Occupations: 12 No. of Employees: 24076 (estimated) No. of Female Employees: 2595 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R20/22
[ RIDADR ]:
UN 3335
[ WGK Germany ]:
3
[ RTECS ]:
DC1925000
[ HS Code ]:
2930909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Toxicol. Appl. Pharmacol. 112(2) , 229-34, (1992)
Hexachlorobenzene (HCB) induces hepatic porphyria and liver cancer in female rats, whereas toxicity is minimal in male rats. HCB is biotransformed to sulfur-containing metabolites originating from con...
Effect of estradiol on the induction of porphyria by hexachlorobenzene in the rat.Biochem. Pharmacol. 54(1) , 19-25, (1997)
Hexachlorobenzene (HCB) is porphyrinogenic in adult female but not in male rats. This study aimed to assess the role of 17beta-estradiol in the induction of porphyria by HCB in both sexes by adding or...
Conversion products of hexachlorobenzene and their role in the disturbance of the porphyrin pathway in rats.Int. J. Biochem. 12(5-6) , 1003-6, (1980)