Meglumine antimonate
Names
[ CAS No. ]:
133-51-7
[ Name ]:
Meglumine antimonate
[Synonym ]:
Methylglucamine antimonate
2168-rp
Protostib {Antimonate}
D-Glucitol, 1-deoxy-1-(methylamino)-, compd. with trihydroxystibine, oxide (1:1)
glucantime
D-Glucitol, 1-deoxy-1-(methylamino)-, compd. with antimonic acid (1:1)
RP 2168 {Antimonate}
protostib
MFCD01725422
Antimonic acid - 1-deoxy-1-(methylamino)-D-glucitol (1:1)
N-Methylglucamine antimonate
N-METHYL GLUCAMINE ANTIMONATE
N-MethylgluamineAntimoniate
meglumineantimonate
Meglumine antimonate
MEGLUMINANTIMONIATE
EINECS 205-108-3
methylglucamineantimonate
Chemical & Physical Properties
[ Density]:
1.375g/cm3
[ Boiling Point ]:
490.4ºC at 760mmHg
[ Melting Point ]:
168-170°C
[ Molecular Formula ]:
C7H18NO8Sb
[ Molecular Weight ]:
383.995
[ Flash Point ]:
251.6ºC
[ Exact Mass ]:
383.017639
[ PSA ]:
167.55000
[ Storage condition ]:
2-8°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LZ4370000
- CHEMICAL NAME :
- D-Glucitol, 1-deoxy-1-(methylamino)-, trioxoantimonate(1-)
- CAS REGISTRY NUMBER :
- 133-51-7
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H17-N-O5.H-O3-Sb
- MOLECULAR WEIGHT :
- 366.01
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Human - child
- DOSE/DURATION :
- 700 mg/kg/7D
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - interstitial nephritis Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - urine volume decreased
- REFERENCE :
- MAMEA2 Maroc Medical. (Casablanca, Morocco) V.1-55, 1921-75. Discontinued. Volume(issue)/page/year: 41,1180,1962 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 27056 mg/kg/30D-I
- TOXIC EFFECTS :
- Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- REFERENCE :
- HETOEA Human & Experimental Toxicology. (Macmillan Press Ltd., Brunel Road, Houndmills, Basingstoke, Hampshire, RG21 2XS, UK) V.9- 1990- Volume(issue)/page/year: 11,283,1992
Safety Information
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .
[ Safety Phrases ]:
S26-S36/37/39